Lineage-specific chimerism monitoring after allogeneic haematopoietic stem cell transplantation: do we really know what we are measuring?

Mark B Watson; Hazel J Clouston; John A Snowden; Gill Wilson; Miranda Durkie; Rosalie Ward; Harpreet Kaur; Debbie Travis; David Barnett

doi:10.1111/bjh.13935

Lineage-specific chimerism monitoring after allogeneic haematopoietic stem cell transplantation: do we really know what we are measuring?

Br J Haematol. 2017 Jan;176(1):139-141. doi: 10.1111/bjh.13935. Epub 2016 Feb 5.

Authors

Mark B Watson^{1

2}, Hazel J Clouston^{1

2}, John A Snowden^{3

4

2}, Gill Wilson^{1

2}, Miranda Durkie^{1

2}, Rosalie Ward^{3

2

5}, Harpreet Kaur^{3

2}, Debbie Travis^{4

2}, David Barnett^{3

4

2

5}

Affiliations

¹ Sheffield Diagnostic Genetics Service, Sheffield Children's NHS Foundation Trust, Sheffield, UK.
² Haemato-oncology Diagnostic Service (HODS), Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
³ Department of Haematology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
⁴ UKNEQAS for Leucocyte Immunophenotyping, Sheffield, UK.
⁵ Department of Haematology, Laboratory Medicine Directorate, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

PMID: 26848116
DOI: 10.1111/bjh.13935

No abstract available

Keywords: CD3+ T-lymphocyte purity; allogeneic haematopoietic stem cell transplantation; lineage-specific chimerism.

MeSH terms

Chimerism
Female
Hematopoietic Stem Cell Transplantation / methods*
Humans
Male
Transplantation Conditioning / methods*
Transplantation Conditioning / mortality
Transplantation, Homologous / methods*