Suppurative Granulomatous Cholecystitis in a Pediatric Chronic Carrier with Salmonella enterica serotype Typhi: A Case Report and Review of Literature

Fetal Pediatr Pathol. 2016;35(2):129-32. doi: 10.3109/15513815.2015.1131784. Epub 2016 Feb 2.

Abstract

Bacterial infection of Salmonella enterica serotype Typhi is rare in the United States but endemic in many developing countries. Approximately 3-5% of patients become chronic asymptomatic carriers. We describe an atypical presentation of S. enterica serotype Typhi infection in a 10-year-old male, whose cholecystechtomy and bile culture revealed chronic carrier status despite negative stool tests and the absence of gallstones. The gallbladder showed marked thickening of the wall with an intense suppurative granulomatous reaction.

Keywords: Cholecystitis; Chronic Carrier; Salmonella enterica serotype Typhi.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Carrier State / microbiology*
  • Carrier State / pathology
  • Child
  • Cholecystitis / microbiology*
  • Cholecystitis / pathology
  • Granuloma / microbiology
  • Granuloma / pathology
  • Humans
  • Male
  • Salmonella typhi*
  • Typhoid Fever / pathology*