Nephrectomy for Non-neoplastic Kidney Diseases

Surg Pathol Clin. 2014 Sep;7(3):307-19. doi: 10.1016/j.path.2014.04.010. Epub 2014 Jul 15.

Abstract

This review discusses the pathology of non-neoplastic kidney disease that pathologists may encounter as nephrectomy specimens. The spectrum of pediatric disease is emphasized. Histopathologic assessment of non-neoplastic nephrectomy specimens must be interpreted in the clinical context for accurate diagnosis. Although molecular pathology is not the primary focus of this review, the genetics underlying several of these diseases are also touched on.

Keywords: ADPKD; ARPKD; Chronic pyelonephritis; Dysplasia; Obstructive nephropathy; Reflux nephropathy; Xanthogranulomatous pyelonephritis.

Publication types

  • Review