Site-specific mutagenesis with unnatural amino acids

Trends Biochem Sci. 1989 Oct;14(10):400-3. doi: 10.1016/0968-0004(89)90287-9.

Abstract

The incorporation of unnatural amino acids into proteins by site-specific mutagenesis provides a valuable new methodology for the generation of novel proteins that possess unique structural and functional features.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Acylation
  • Amino Acids
  • Mutation*
  • Proteins / genetics*
  • RNA, Transfer / genetics
  • Suppression, Genetic
  • beta-Lactamases / genetics

Substances

  • Amino Acids
  • Proteins
  • RNA, Transfer
  • beta-Lactamases