FDG PET/CT Evidence of Effective Treatment of Cardiac Sarcoidosis With Adalimumab

Clin Nucl Med. 2016 May;41(5):417-8. doi: 10.1097/RLU.0000000000001124.

Abstract

A 53-year-old man with mediastinal lymph node biopsy and cardiac MRI-proven cardiac sarcoidosis (CS) received treatment with pacemaker and steroids. FDG PET/CT showed active CS despite treatment with prednisone and methotrexate. Addition of weekly adalimumab (Humira) injections was introduced for 3 months. Follow-up FDG PET/CT showed complete resolution of CS as well as improvement of other sarcoid lesions in the thoracic lymph nodes.

Publication types

  • Case Reports

MeSH terms

  • Adalimumab / therapeutic use*
  • Anti-Inflammatory Agents / therapeutic use*
  • Cardiomyopathies / diagnostic imaging
  • Fluorodeoxyglucose F18
  • Humans
  • Male
  • Middle Aged
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Sarcoidosis / diagnostic imaging
  • Sarcoidosis / drug therapy*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Adalimumab