Dynamic modulation of rTMS on functional connectivity and functional network connectivity to children with cerebral palsy: a case report

Neuroreport. 2016 Mar 2;27(4):284-8. doi: 10.1097/WNR.0000000000000534.

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive treatment tool for the recovery of cerebral palsy (CP). This report describes the modulation effect of rTMS to functional connectivity, functional network connectivity, motor, and cognitive ability following treatment in a child with mild ataxia CP. After receiving 8 months of 0.5 Hz rTMS treatment over the right dorsolateral prefrontal cortex, the child showed a gradual improvement in motor and cognitive-related functional connectivity and functional network connectivity following treatment as well as improved motor, cognitive functions. These pilot results provide the first evidence of the efficiency of 0.5 Hz of rTMS on a child with CP. Further large sample studies are needed to verify and expand the present findings.

Publication types

  • Case Reports

MeSH terms

  • Cerebral Palsy / physiopathology*
  • Cerebral Palsy / psychology
  • Cerebral Palsy / rehabilitation*
  • Child
  • Cognition / physiology
  • Humans
  • Male
  • Motor Activity / physiology
  • Neural Pathways / physiopathology
  • Pilot Projects
  • Prefrontal Cortex / physiopathology*
  • Transcranial Magnetic Stimulation / methods*
  • Treatment Outcome