Building a hit list for the fight against metastatic castration resistant prostate cancer

Cancer Biol Ther. 2016;17(3):231-2. doi: 10.1080/15384047.2016.1139270. Epub 2016 Jan 29.

Abstract

Identification of genetic alterations in Metastatic Castration Resistant Prostate Cancer (mCRPC) may provide scientists and clinicians with a list of new targets for drug research and development. Recently published in Cell, Robinson et al. present the first look at genetic data from mCRPC lesions gathered over multiple years and from many institutions.

Keywords: Actionable tumors; PTEN; androgen deprivation; androgen receptor; genetic alterations; mCRPC; translational medication.

Publication types

  • Comment

MeSH terms

  • Gene Expression Profiling / methods*
  • Humans
  • Male
  • Prostatic Neoplasms, Castration-Resistant / genetics*
  • Prostatic Neoplasms, Castration-Resistant / pathology*