Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer?

Carlos Sanhueza; Joaquín Araos; Luciano Naranjo; Eric Barros; Lilian Toledo; Mario Subiabre; Fernando Toledo; Jaime Gutiérrez; Delia I Chiarello; Fabián Pardo; Andrea Leiva; Luis Sobrevia

doi:10.1016/j.phrs.2016.01.007

Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer?

Pharmacol Res. 2016 Mar:105:183-5. doi: 10.1016/j.phrs.2016.01.007. Epub 2016 Jan 26.

Authors

Affiliations

¹ Cellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, P.O. Box 114-D, Santiago 8330024, Chile. Electronic address: csanhuezamunoz@gmail.com.
² Cellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, P.O. Box 114-D, Santiago 8330024, Chile.
³ Department of Basic Sciences, Faculty of Sciences, Universidad del Bío-Bío, Chillán 3780000, Chile.
⁴ Cellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, P.O. Box 114-D, Santiago 8330024, Chile; Cellular Signalling and Differentiation Laboratory (CSDL), School of Medical Technology, Health Sciences Faculty, Universidad San Sebastian, Santiago 7510157, Chile.
⁵ Cellular and Molecular Physiology Laboratory (CMPL), Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, P.O. Box 114-D, Santiago 8330024, Chile; Department of Physiology, Faculty of Pharmacy, Universidad de Sevilla, Seville E-41012, Spain; University of Queensland Centre for Clinical Research (UQCCR), Faculty of Medicine and Biomedical Sciences, University of Queensland, Herston, Queensland, QLD 4029, Australia. Electronic address: sobrevia@med.puc.cl.

PMID: 26821117
DOI: 10.1016/j.phrs.2016.01.007

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Cation Transport Proteins / metabolism*
Female
Humans
Nitric Oxide / metabolism*
Nitric Oxide Synthase Type II / genetics
Nitric Oxide Synthase Type II / metabolism*
Ovarian Neoplasms / genetics
Ovarian Neoplasms / metabolism*
Ovarian Neoplasms / pathology
Ovary / metabolism*
Ovary / pathology
Sodium-Hydrogen Exchanger 1
Sodium-Hydrogen Exchangers / metabolism*
Up-Regulation

Substances

Cation Transport Proteins
SLC9A1 protein, human
Sodium-Hydrogen Exchanger 1
Sodium-Hydrogen Exchangers
Nitric Oxide
NOS2 protein, human
Nitric Oxide Synthase Type II