Overcoming Challenges With Statin Therapy

J Am Heart Assoc. 2016 Jan 27;5(1):e002497. doi: 10.1161/JAHA.115.002497.

Authors

J David Spence¹, George K Dresser²

Affiliations

¹ Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada (D.S.) Division of Clinical Pharmacology, Department of Medicine, Western University, London, Ontario, Canada (D.S., G.K.D.).
² Division of Clinical Pharmacology, Department of Medicine, Western University, London, Ontario, Canada (D.S., G.K.D.).

No abstract available

Keywords: Persistence; adverse effects; mitochondrial function; statins; ubiquinone.

Publication types

Case Reports
Review

MeSH terms

Biomarkers / blood
Cardiovascular Diseases / blood
Cardiovascular Diseases / etiology
Cardiovascular Diseases / prevention & control*
Diabetes Mellitus / chemically induced*
Drug Interactions
Drug Substitution
Dyslipidemias / blood
Dyslipidemias / complications
Dyslipidemias / drug therapy*
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacokinetics
Insulin Resistance*
Lipids / blood*
Male
Medication Adherence
Middle Aged
Muscular Diseases / chemically induced*
Pharmacogenetics
Practice Patterns, Physicians'
Risk Factors
Treatment Outcome

Substances

Biomarkers
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipids