Treatment of Diffuse Pulmonary Hemorrhage with Factor VIIa

Jens Schreiber; Frank Lautenschlaeger; Stefan Breuer; Joachim Zagrodnick; Reiner Kachel; Reinhard Schueck

doi:10.1007/s00068-008-7104-2

Treatment of Diffuse Pulmonary Hemorrhage with Factor VIIa

Eur J Trauma Emerg Surg. 2008 Jun;34(3):315-8. doi: 10.1007/s00068-008-7104-2. Epub 2008 Feb 20.

Authors

Jens Schreiber^{1

2}, Frank Lautenschlaeger³, Stefan Breuer³, Joachim Zagrodnick⁴, Reiner Kachel⁵, Reinhard Schueck⁶

Affiliations

¹ Department of Pulmonology, University Hospital Magdeburg, Magdeburg, Germany. jens.schreiber@med.ovgu.de.
² Department of Pulmonology, University Hospital Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany. jens.schreiber@med.ovgu.de.
³ Department of Anesthesiology and Intensive Care Medicine, Dessau Medical Center, Dessau, Germany.
⁴ Department of Traumatology, Dessau Medical Center, Dessau, Germany.
⁵ Department of Diagnostic and Interventional Radiology/Neuroradiology and Nuclear Medicine, Dessau Medical Center, Dessau, Germany.
⁶ Department of Surgery/Thoracic Surgery, Dessau Medical Center, Dessau, Germany.

PMID: 26815758
DOI: 10.1007/s00068-008-7104-2

Abstract

Blunt thoracic trauma resulting in lung contusion with severe diffuse pulmonary hemorrhage and massive hemoptysis is rare and has a poor prognosis. Treatment options are limited. We report a case of the successful use of recombinant activated factor VII (NovoSeven™) in the treatment of life-threatening diffuse pulmonary hemorrhage secondary to an isolated blunt force thoracic injury without relevant traumatic coagulopathy.

Keywords: Chest trauma; Diffuse pulmonary hemorrhage; Factor VIIa; Lung contusion.