Abstract
A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013. Comparison with a French strain that was pertussis toxin-deficient, pertactin wild-type showed that the strains carry the same 28-kb deletion in similar genomes.
Keywords:
Bordetella pertussis; Pertussis; pertactin; pertussis toxin.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Outer Membrane Proteins / genetics*
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Bacterial Outer Membrane Proteins / immunology
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Bacterial Outer Membrane Proteins / metabolism
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Bordetella pertussis / genetics*
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Bordetella pertussis / immunology
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Bordetella pertussis / metabolism
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Gene Deletion
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Humans
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Pertussis Toxin / genetics*
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Pertussis Toxin / immunology
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Pertussis Toxin / metabolism
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Pertussis Vaccine / genetics
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Pertussis Vaccine / immunology
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Virulence Factors, Bordetella / genetics*
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Virulence Factors, Bordetella / immunology
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Virulence Factors, Bordetella / metabolism
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Whooping Cough / prevention & control
Substances
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Bacterial Outer Membrane Proteins
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Pertussis Vaccine
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Virulence Factors, Bordetella
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pertactin
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Pertussis Toxin