Applications of cyclodextrins in medical textiles - review

Abstract

This paper presents data on the general properties and complexing ability of cyclodextrins and assessment methods (phase solubility, DSC tests and X-ray diffraction, FTIR spectra, analytical method). It focuses on the formation of drug deposits on the surface of a textile underlayer, using a cyclodextrin compound favoring the inclusion of a drug/active principle and its release onto the dermis of patients suffering from skin disorders, or for protection against insects. Moreover, it presents the kinetics, duration, diffusion flow and release media of the cyclodextrin drug for in vitro studies, as well as the release modeling of the active principle. The information focuses on therapies: antibacterial, anti-allergic, antifungal, chronic venous insufficiency, psoriasis and protection against insects. The pharmacodynamic agents/active ingredients used on cotton, woolen and synthetic textile fabrics are presented.

Keywords: Acryloyl chloride (PubChem CID: 13140); Ag (PubChem CID: 23954); Beta-Cyclodextrin (PubChem CID: 71306822); Cyclodextrin; Drug release; Epichlorohydrin (PubChem CID: 7835); Itaconic acid (PubChem CID: 811); Methyl-Beta-cyclodextrin (PubChem CID: 51051622); Permethrin (PubChem CID: 40326); Polyhexamethylene biguanide (PubChem CID: 20977); Skin disorders; Textile fabric; Triclosan (PubChem CID: 5564).