Data for identification of porcine X-chromosome inactivation center, XIC, by genomic comparison with human and mouse XIC

Jae Yeon Hwang; Kwang-Hwan Choi; Chang-Kyu Lee

doi:10.1016/j.dib.2015.11.019

Data for identification of porcine X-chromosome inactivation center, XIC, by genomic comparison with human and mouse XIC

Data Brief. 2015 Nov 29:5:1072-7. doi: 10.1016/j.dib.2015.11.019. eCollection 2015 Dec.

Authors

Jae Yeon Hwang¹, Kwang-Hwan Choi¹, Chang-Kyu Lee²

Affiliations

¹ Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 151-921, Republic of Korea.
² Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 151-921, Republic of Korea; Designed Animal & Transplantation Research Institute, Institute of Green Bio Science and Technology, Seoul National University, Gangwon-do 232-916, Republic of Korea.

Abstract

The data included in this article shows homologies of genes in porcine X-chromosome inactivation center, XIC, to each orthologue in human and mouse XIC. Open sequences of XIC-linked genes in human and mouse were compared to porcine genome and sequence homology of each orthologue to porcine genome was calculated. Sequence information of porcine genes encoded in the genomic regions having sequence homology with the human XIC-linked genes and their 2 Kb upstream regions were downloaded. Obtained information was used to design primer pairs for expression and methylation pattern analyses of XIC-linked genes in pigs. The data represented in here is related and applied to the research article entitled "Dosage compensation of X-chromosome inactivation center, XIC,-linked genes in porcine preimplantation embryos: Non-chromosome wide initiation of X-chromosome inactivation in blastocysts", published in Mechanisms of Development Hwang et al., 2015 [1].