Growing Renal Mass: Lessons Learned on the Road From an Atypical Presentation to Successful Therapy

Eliza Lamin; Dana A Weiss; Kassa Darge; Fumiko Dekio; Douglas A Canning

doi:10.1016/j.eucr.2015.06.001

Growing Renal Mass: Lessons Learned on the Road From an Atypical Presentation to Successful Therapy

Urol Case Rep. 2015 Jun 26;3(5):157-60. doi: 10.1016/j.eucr.2015.06.001. eCollection 2015 Sep.

Authors

Eliza Lamin¹, Dana A Weiss², Kassa Darge³, Fumiko Dekio⁴, Douglas A Canning⁵

Affiliations

¹ Division of Urology, University of Pennsylvania Health System, Philadelphia, USA.
² Division of Urology, The Children's Hospital of Philadelphia, Philadelphia, USA; Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, USA.
³ Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, USA.
⁴ Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, USA.
⁵ Division of Urology, The Children's Hospital of Philadelphia, Philadelphia, USA.

Abstract

A 25 4/7 week boy was born with a prenatal diagnosis of polyhydramnios and enlarged left kidney. Over the next 2 months serial ultrasounds demonstrated abnormal growth of the kidney, with 28.9% split function. At gestational age 39 4/7, he underwent a left radical nephrectomy. Pathology revealed congenital mesoblastic nephroma with mixed classic and cellular features. This case was puzzling due to prenatally diagnosed renal enlargement in a premature infant and inconclusive post-natal ultrasonographic imaging. Although the patient had paraneoplastic signs of polyhydramnios and hypertension, the mass did not have a classic appearance of CMN; possibly due to severe prematurity.

Keywords: CMN, congenital mesoblastic nephroma; Congenital mesoblastic nephroma; Peak systolic velocity; RVT, renal venous thrombosis; Renal masses; Renal venous thrombosis; US, ultrasound.

Publication types

Case Reports