Peripartum cardiomyopathy in Turkey: Experience of three tertiary centres

J Obstet Gynaecol. 2016 Jul;36(5):574-80. doi: 10.3109/01443615.2015.1107531. Epub 2016 Jan 20.

Abstract

We conducted this study to determine demographic details, and clinical presentations in patients with peripartum cardiomyopathy (PPCMP) of Turkish origin. The study population consisted of 58 patients with PPCMP treated at 3 major hospitals in Turkey, retrospectively. In this study, demographic details and initial echocardiographic data were recorded and long-term clinical status was evaluated. The mean age for the patient cohort was 31.47 ± 6.31 years. Thirty-eight patients (73.1%) were multigravida and seven patients had multifetal pregnancy (13.7%). The mean follow-up left ventricular (LV) ejection fraction increased from 31 ± 7 to 38 ± 19. A minority of patients were defined as improvers according to our pre-specified criteria. The average survival period after diagnosis of PPCMP was 20.66 ± 14.44 months. Initial values for LV end-diastolic diameter and urea were higher in the deceased patients compared with the surviving patients, respectively. Twenty-eight (48%) patients with PPCMP showed improvement in the follow-up period. Of the 58 PPCMP patients, 9 (15%) died during a mean follow-up of 32 ± 22 months.

Keywords: Heart failure; peripartum cardiomyopathy; pregnancy; systolic dysfunction.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Cardiomyopathies / mortality*
  • Cardiomyopathies / physiopathology
  • Echocardiography
  • Female
  • Follow-Up Studies
  • Gravidity
  • Humans
  • Peripartum Period*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / mortality*
  • Pregnancy Complications, Cardiovascular / physiopathology
  • Pregnancy, Multiple
  • Puerperal Disorders / mortality*
  • Puerperal Disorders / physiopathology
  • Retrospective Studies
  • Survival Rate
  • Tertiary Care Centers
  • Turkey / epidemiology
  • Ventricular Function, Left