Long-term follow-up of large symptomatic hepatic cysts treated by percutaneous ethanol sclerotherapy

Acta Radiol. 2016 Oct;57(10):1205-9. doi: 10.1177/0284185115626476. Epub 2016 Jan 18.

Abstract

Background: As a minimally invasive treatment, ethanol sclerotherapy has been used for large symptomatic hepatic cysts, but there are not many long-term reports on treatment outcomes and safety.

Purpose: To evaluate the long-term outcomes of percutaneous ethanol sclerotherapy in patients with large symptomatic hepatic cysts.

Material and methods: This study included 43 symptomatic, enlarging hepatic cysts in 42 patients who had undergone ethanol sclerotherapy from 2003 to 2013 and were followed up for >1 year. The treatment outcomes were evaluated in terms of the reduction of cyst size and resolution of symptoms. The patients were followed up for a mean period of 33 months with either ultrasound or computed tomography examination.

Results: Thirty-nine hepatic cysts (91%) were successfully treated with ethanol sclerotherapy, showing resolution of symptoms and remarkable reduction in cyst volume. Eight hepatic cysts (19%) disappeared completely, and 31 hepatic cysts (72%) decreased in size during the follow-up period. The mean diameter of the cysts decreased from 12.5 ± 4.4 cm to 3.8 ± 3.4 cm during follow-up. There were no immediate serious complications related to the procedure. There were four cases (9%) of treatment failure requiring subsequent surgical procedures.

Conclusion: Percutaneous ethanol sclerotherapy can be considered as an effective first-line treatment for large symptomatic hepatic cysts.

Keywords: Hepatic cyst; ethanol; multiple sessions; percutaneous; sclerotherapy; single prolonged session.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cysts / diagnostic imaging
  • Cysts / therapy*
  • Diagnostic Imaging
  • Ethanol / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Liver Diseases / diagnostic imaging
  • Liver Diseases / therapy*
  • Male
  • Middle Aged
  • Sclerosing Solutions / therapeutic use*
  • Sclerotherapy / methods*
  • Treatment Outcome

Substances

  • Sclerosing Solutions
  • Ethanol