Zika fever imported from Thailand to Japan, and diagnosed by PCR in the urines

J Travel Med. 2016 Jan 18;23(1):tav011. doi: 10.1093/jtm/tav011. Print 2016 Jan.

Abstract

In July 2014, a Japanese traveller returning from Thailand was investigated for fever, headache, rash and conjunctivitis. Zika virus RNA was detected in his urine sample by real-time reverse transcription polymerase chain reaction. Serological tests showed cross reactivity of IgM against the dengue virus. Zika fever could be misdiagnosed or missed and should be considered in febrile patients with a rash, especially those returning from Thailand.

Keywords: Flaviviridae; Mosquito-borne disease; Zika fever.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Dengue Virus
  • Exanthema / virology
  • Fever / virology
  • Humans
  • Immunoglobulin M / blood*
  • Japan
  • Male
  • RNA, Viral / urine*
  • Real-Time Polymerase Chain Reaction
  • Thailand
  • Travel*
  • Zika Virus / isolation & purification
  • Zika Virus Infection / diagnosis*

Substances

  • Immunoglobulin M
  • RNA, Viral