Fight, Flight, or Freeze? The Answer May Depend on Your Sex

Carolyn E Jones; Marie-H Monfils

doi:10.1016/j.tins.2015.12.010

Fight, Flight, or Freeze? The Answer May Depend on Your Sex

Trends Neurosci. 2016 Feb;39(2):51-53. doi: 10.1016/j.tins.2015.12.010. Epub 2016 Jan 6.

Authors

Carolyn E Jones¹, Marie-H Monfils²

Affiliations

¹ Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA.
² Department of Psychology, University of Texas at Austin, 1 University Station, A8000 Austin, TX 78712, USA. Electronic address: marie.monfils@utexas.edu.

PMID: 26776563
DOI: 10.1016/j.tins.2015.12.010

Abstract

Pavlovian fear conditioning is one of the most common and well-understood methods for studying fear learning. However, research is predominantly performed in males. Recently, in a classical Pavlovian fear conditioning paradigm, Gruene and colleagues described an active conditioned fear response ('darting') prevalent in female rats that better maintain an extinction memory.

Keywords: escape; fear conditioning; females; sex differences.

Publication types

Comment

MeSH terms

Animals
Fear*
Female
Locomotion*
Male

Grants and funding

R01 MH091147/MH/NIMH NIH HHS/United States