[Diabetes and type of diet as determinant factor in the progression of atherosclerosis]

Arch Cardiol Mex. 2016 Oct-Dec;86(4):326-334. doi: 10.1016/j.acmx.2015.12.003. Epub 2016 Jan 14.
[Article in Spanish]

Abstract

The purpose of this review is to analyze the biochemical progression of atherosclerotic plaque and its association with diet and diabetes. This study shows the scientific evidence of demonstrating that diabetic patients present high levels of fatty acids like palmitic acid and linoleic acid in their atheroma plaques in comparison with non-diabetic patients. This study also establishes how patients with diabetes mellitus have a higher prevalence of atherosclerotic heart diseases in the form of Coronary Thrombosis and have different anatomopathological appearance like higher necrotic core and thin fibrotic layer than the general population. Furthermore this review describes the different anatomopathological appearance and cellular changes involved in the formation of these plaques and how diet can affect the development of these plaques.

Keywords: Alimentación; Aterosclerosis; Atherosclerosis; Diabetes mellitus; Fatty acids; Food intake; Mexico; México; Ácidos grasos.

Publication types

  • Review

MeSH terms

  • Atherosclerosis / etiology*
  • Diabetes Complications / etiology*
  • Diet / adverse effects*
  • Disease Progression
  • Humans
  • Plaque, Atherosclerotic / etiology*