Nanotransporters for drug delivery

Curr Opin Biotechnol. 2016 Jun:39:35-40. doi: 10.1016/j.copbio.2015.12.013. Epub 2016 Jan 11.

Abstract

Soluble nanotransporters for drugs can be profiled for targeted delivery particularly to maximize the efficacy of highly potent drugs while minimizing off target effects. This article outlines on the use of biological carrier molecules with a focus on albumin, various drug linkers for site specific release of the drug payload from the nanotransporter and strategies to combine these in various ways to meet different drug delivery demands particularly the optimization of the payload per nanotransporter.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Carriers / chemistry*
  • Drug Delivery Systems / methods*
  • Enzymes / metabolism
  • Humans
  • Nanoparticles / chemistry*

Substances

  • Drug Carriers
  • Enzymes