Pyoderma gangrenosum-like oral ulcerations in an elderly patient

Gerodontology. 2015 Dec;32(4):309-13. doi: 10.1111/ger.12158.

Abstract

Objective: To present a case of pyoderma gangrenosum (PG)-like oral ulcerations in an elderly patient.

Background: PG is an uncommon idiopathic, ulcerative, chronic inflammatory cutaneous disorder of unknown etiology, which is associated with systemic diseases found in more than 50% of patients. Oral lesions of PG are extremely rare and have not been previously reported on chronic leukemia patient.

Clinical report: This report presents the first case of a 73 year-old man who had PG-like oral ulcerations which offered the possibility of an initial finding of chronic myeloid leukemia.

Conclusion: Clinicians should always take into consideration that PG in the oral mucosa is a recalcitrant ulcer and can precede the development of underlying clonal malignancy.

Keywords: leukaemia; oral ulceration; pyoderma gangrenosum.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy
  • Diagnosis, Differential
  • Humans
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
  • Male
  • Mouth Diseases / pathology*
  • Mouth Mucosa / pathology*
  • Oral Ulcer / pathology*
  • Pyoderma Gangrenosum / diagnosis
  • Pyoderma Gangrenosum / pathology*
  • Rare Diseases / diagnosis
  • Thailand