A Case of Solitary Kidney Atrophy Due to Primary Hyperparathyroidism: A Case Report

Medicine (Baltimore). 2016 Jan;95(2):e2449. doi: 10.1097/MD.0000000000002449.

Abstract

Although primary hyperparathyroidism (PHPT) is asymptomatic in most patients, its main clinical manifestation is nephrolithiasis. In general, hypercalcemia would lead to unilateral renal stones, which may become bilateral over time. We present a rare case of a large unilateral asymptomatic ureteral stone in a patient with hypercalcemia secondary to PHPT, which eventually led to renal atrophy.The diagnosis of PHPT should be considered in patients with hypercalcemia and renal stones, as asymptomatic PHPT may result in a devastating renal outcome.

Publication types

  • Case Reports

MeSH terms

  • Atrophy / pathology
  • Atrophy / surgery
  • Contrast Media
  • Female
  • Follow-Up Studies
  • Humans
  • Hydronephrosis / diagnosis
  • Hydronephrosis / etiology
  • Hypercalcemia / diagnosis
  • Hypercalcemia / etiology
  • Hyperparathyroidism, Primary / complications
  • Hyperparathyroidism, Primary / diagnostic imaging*
  • Hyperparathyroidism, Primary / surgery*
  • Kidney / pathology*
  • Kidney / surgery
  • Middle Aged
  • Nephrectomy / methods
  • Nephrolithiasis / complications
  • Nephrolithiasis / diagnosis*
  • Nephrolithiasis / surgery
  • Parathyroidectomy / methods
  • Positron-Emission Tomography / methods
  • Risk Assessment
  • Thyroidectomy / methods
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome

Substances

  • Contrast Media