Nanog dynamics in single embryonic stem cells

Cell Cycle. 2016;15(6):770-1. doi: 10.1080/15384101.2015.1137711.
No abstract available

Keywords: cell-to-cell-heterogeneity; differentiation propensity; embryonic stem cells; nanog; pluripotency; protein expression dynamics; single-cell analysis; time-lapse-imaging; transcription factor networks.

MeSH terms

  • Animals
  • Cell Cycle / genetics*
  • Cell Differentiation
  • Gene Expression Regulation, Developmental*
  • Humans
  • Kruppel-Like Factor 4
  • Kruppel-Like Transcription Factors / genetics
  • Kruppel-Like Transcription Factors / metabolism
  • Mice
  • Mouse Embryonic Stem Cells / classification
  • Mouse Embryonic Stem Cells / cytology
  • Mouse Embryonic Stem Cells / metabolism*
  • Nanog Homeobox Protein / genetics*
  • Nanog Homeobox Protein / metabolism
  • Octamer Transcription Factor-3 / genetics
  • Octamer Transcription Factor-3 / metabolism
  • SOXB1 Transcription Factors / genetics
  • SOXB1 Transcription Factors / metabolism
  • Signal Transduction
  • Single-Cell Analysis

Substances

  • Kruppel-Like Factor 4
  • Kruppel-Like Transcription Factors
  • Nanog Homeobox Protein
  • Nanog protein, mouse
  • Octamer Transcription Factor-3
  • Pou5f1 protein, mouse
  • SOXB1 Transcription Factors
  • Sox2 protein, mouse