Intravertebral vacuum cleft sign: a cause of vertebral cold defect on bone scan

Skeletal Radiol. 2016 May;45(5):707-12. doi: 10.1007/s00256-016-2331-9. Epub 2016 Jan 13.

Abstract

A 67-year-old female presented with an acute compression fracture with an intravertebral vacuum cleft (IVC) sign of the T12 vertebra. Her bone scan demonstrated a cold defect of the fractured vertebra. Although the IVC sign is related to vertebral osteonecrosis, to the best of our knowledge, a cold defect on a bone scan has not been reported in an acute compression fracture with an IVC sign. In this case review, various imaging findings of osteonecrotic compression fractures are discussed along with a review of the current literature.

Keywords: Bone scan; Cold defect; Compression fracture; Intravertebral vacuum; Osteonecrosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Diagnosis, Differential
  • Female
  • Fractures, Compression / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Osteonecrosis / diagnostic imaging*
  • Positron Emission Tomography Computed Tomography / methods
  • Spinal Fractures / diagnostic imaging*
  • Thoracic Vertebrae / diagnostic imaging
  • Thoracic Vertebrae / injuries*