Multiband RF pulses with improved performance via convex optimization

J Magn Reson. 2016 Jan:262:81-90. doi: 10.1016/j.jmr.2015.11.010. Epub 2015 Dec 14.

Abstract

Selective RF pulses are commonly designed with the desired profile as a low pass filter frequency response. However, for many MRI and NMR applications, the spectrum is sparse with signals existing at a few discrete resonant frequencies. By specifying a multiband profile and releasing the constraint on "don't-care" regions, the RF pulse performance can be improved to enable a shorter duration, sharper transition, or lower peak B1 amplitude. In this project, a framework for designing multiband RF pulses with improved performance was developed based on the Shinnar-Le Roux (SLR) algorithm and convex optimization. It can create several types of RF pulses with multiband magnitude profiles, arbitrary phase profiles and generalized flip angles. The advantage of this framework with a convex optimization approach is the flexible trade-off of different pulse characteristics. Designs for specialized selective RF pulses for balanced SSFP hyperpolarized (HP) (13)C MRI, a dualband saturation RF pulse for (1)H MR spectroscopy, and a pre-saturation pulse for HP (13)C study were developed and tested.

Keywords: Convex optimization; Generalized flip angle; Improved pulse performance; Multiband; RF pulse design; Shinnar–Le Roux algorithm.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Brain
  • Calibration
  • Carbon Isotopes
  • Humans
  • Lactates / chemistry
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Spectroscopy / methods*
  • Phantoms, Imaging
  • Protons
  • Pyruvates / chemistry
  • Radio Waves*
  • Urea / chemistry

Substances

  • Carbon Isotopes
  • Lactates
  • Protons
  • Pyruvates
  • Urea