[Long-term follow-up of patients with transposition of the great arteries following Senning or Mustard operations. Results from the CSONGRAD Registry]

Orv Hetil. 2016 Jan 17;157(3):104-10. doi: 10.1556/650.2015.30337.
[Article in Hungarian]

Abstract

Introduction: Transposition of the great arteries is one of the most common cyanotic congenital heart diseases.

Aim: The present study aimed to examine and compare long-term survival, functional grading, arrhytmologic and quality of life control in patients with transposition of the great arteries following Senning- and Mustard-operations.

Methods: The present study comprised 85 patients with transposition of the great arteries, of whom Senning-operation was performed in 37 cases and Mustard-operation in 48 subjects. Follow-up study was performed in all cases.

Results: The success rate of long-term follow-up proved to be 74%. Twelve out of the 31 Senning-operated and 16 out of 32 Mustard-operated patients died during the follow-up (39% vs. 50%, p = 0.45). Neither features of heart failure, nor those of arrhythmias showed differences between the groups, but parameters of quality of life and functional capacity proved to be favourable in Senning-operated patients.

Conclusions: There is no significant difference in mortality and morbidity of patients with transposition of the great arteries following Mustard- and Senning-operations. Regarding to long-term follow-up quality of life and functional capacity of Senning-operated patients were more favourable.

Keywords: follow-up; teljes nagyér-transzpozíció; transposition of the great arteries; utánkövetés.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Arrhythmias, Cardiac / epidemiology
  • Arrhythmias, Cardiac / etiology
  • Arterial Switch Operation / adverse effects*
  • Arterial Switch Operation / methods*
  • Child
  • Child, Preschool
  • Educational Status
  • Employment
  • Female
  • Follow-Up Studies
  • Health Status
  • Heart Failure / epidemiology
  • Heart Failure / etiology
  • Humans
  • Hungary / epidemiology
  • Infant
  • Male
  • Quality of Life
  • Registries
  • Sample Size
  • Survival Analysis
  • Transposition of Great Vessels / mortality*
  • Transposition of Great Vessels / surgery*
  • Treatment Outcome
  • Young Adult