Invasive Candidiasis

Todd P McCarty; Peter G Pappas

doi:10.1016/j.idc.2015.10.013

Invasive Candidiasis

Infect Dis Clin North Am. 2016 Mar;30(1):103-24. doi: 10.1016/j.idc.2015.10.013. Epub 2015 Dec 29.

Authors

Todd P McCarty¹, Peter G Pappas²

Affiliations

¹ University of Alabama at Birmingham, 1900 University Boulevard, 229 THT, Birmingham, AL 35294-0006, USA.
² University of Alabama at Birmingham, 1900 University Boulevard, 229 THT, Birmingham, AL 35294-0006, USA. Electronic address: pappas@uab.edu.

PMID: 26739610
DOI: 10.1016/j.idc.2015.10.013

Abstract

Invasive candidiasis is a collective term that refers to a group of infectious syndromes caused by a variety of species of Candida, 5 of which cause most cases. Candidemia is the most commonly recognized syndrome associated with invasive candidiasis. Certain conditions may influence the likelihood for one species versus another in a specific clinical scenario, and this can have important implications for selection of antifungal therapy and the duration of treatment. Molecular diagnostic technology plays an ever-increasing role as an adjunct to traditional culture-based diagnostics, offering significant potential toward improvement in patient care.

Keywords: Antifungals; Bloodstream infection; Candida; Fungal infection; Invasive candidiasis.

Publication types

Review

MeSH terms

Antifungal Agents / therapeutic use*
Candidiasis, Invasive / diagnosis*
Candidiasis, Invasive / epidemiology
Candidiasis, Invasive / microbiology
Candidiasis, Invasive / therapy*
Echinocandins / therapeutic use*
Humans
Microbial Sensitivity Tests

Substances

Antifungal Agents
Echinocandins