Intraventricular schwannoma in a child. Literature review and case illustration

Childs Nerv Syst. 2016 Jun;32(6):1135-40. doi: 10.1007/s00381-015-2986-x. Epub 2016 Jan 6.

Abstract

Background: Intraventricular schwannoma remains a rare entity in the literature. Controversy exists on the possible pathogenesis of such a tumor within cerebral ventricles. Literature is sparse on tumor characteristics and differences between pediatric and adult patients.

Case report: We present a case of intraventricular schwannoma in a 9-year-old patient presenting with headache, hemiparesis, and focal seizure. Brain CT scan and MRI revealed an intraventricular tumor within left atrium of lateral ventricle. The patient underwent total resection of the tumor via posterior parietal approach. Histopathological exam was in favor of schwannoma. Postoperative brain MRI and MRS showed no recurrence after 18 months.

Conclusion: Our review of the literature indicates there are some significant differences between pediatric and adult cases in different aspects including gender predominance, intraventricular location, malignant transformation, tendency for recurrence, and surgical outcome. This needs to be taken into account in the literature.

Keywords: Brain tumor; Child; Hydrocephalus; Intraventricular; Schwannoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Brain / diagnostic imaging
  • CD57 Antigens / metabolism
  • Cerebral Ventricle Neoplasms / diagnostic imaging
  • Cerebral Ventricle Neoplasms / metabolism
  • Cerebral Ventricle Neoplasms / surgery*
  • Child
  • Glial Fibrillary Acidic Protein / metabolism
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Male
  • Mucin-1 / metabolism
  • Neurilemmoma / diagnostic imaging
  • Neurilemmoma / metabolism
  • Neurilemmoma / surgery*
  • S100 Proteins / metabolism
  • Tomography Scanners, X-Ray Computed

Substances

  • CD57 Antigens
  • Glial Fibrillary Acidic Protein
  • Mucin-1
  • S100 Proteins