Detection of mild Alzheimer's disease and mild cognitive impairment from elderly speech: Binary discrimination using logistic regression

Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug:2015:5569-72. doi: 10.1109/EMBC.2015.7319654.

Abstract

In this research, we have developed a novel data-mining approach for detection of cognitive impairment, SPCIR (Speech Prosody-Based Cognitive Impairment Rating), which can discriminate between mild cognitive impairment and mild Alzheimer's disease from elderly using prosodic sign extracted from elderly speech during questionnaire test. This paper proposes a binary discrimination model of SPCIR using multivariate logistic regression and model selection using receiver operating characteristic (ROC) curve analysis, and reports the sensitivity and specificity of SPCIR for diagnosis (control; mild cognitive impairment/mild Alzheimer's disease).

MeSH terms

  • Aged
  • Alzheimer Disease*
  • Cognitive Dysfunction*
  • Humans
  • Logistic Models
  • Neuropsychological Tests
  • ROC Curve
  • Speech