Path2PPI: an R package to predict protein-protein interaction networks for a set of proteins

Bioinformatics. 2016 May 1;32(9):1427-9. doi: 10.1093/bioinformatics/btv765. Epub 2016 Jan 5.

Abstract

: We introduce Path2PPI, a new R package to identify protein-protein interaction (PPI) networks for fully sequenced organisms for which nearly none PPI are known. Path2PPI predicts PPI networks based on sets of proteins from well-established model organisms, providing an intuitive visualization and usability. It can be used to combine and transfer information of a certain pathway or biological process from several reference organisms to one target organism.

Availability and implementation: Path2PPI is an open-source tool implemented in R. It can be obtained from the Bioconductor project: http://bioconductor.org/packages/Path2PPI/ CONTACT: : ina.koch@bioinformatik.uni-frankfurt.de

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Animals
  • Humans
  • Protein Interaction Maps*
  • Proteins
  • Software*

Substances

  • Proteins