Anemia and transfusion in the neonate

Raffaella Colombatti; Laura Sainati; Daniele Trevisanuto

doi:10.1016/j.siny.2015.12.001

Anemia and transfusion in the neonate

Semin Fetal Neonatal Med. 2016 Feb;21(1):2-9. doi: 10.1016/j.siny.2015.12.001. Epub 2015 Dec 28.

Authors

Raffaella Colombatti¹, Laura Sainati², Daniele Trevisanuto³

Affiliations

¹ Clinic of Pediatric Hematology Oncology, Department of Child and Maternal Health, Azienda Ospedaliera - University of Padova, Padova, Italy. Electronic address: rcolombatti@gmail.com.
² Clinic of Pediatric Hematology Oncology, Department of Child and Maternal Health, Azienda Ospedaliera - University of Padova, Padova, Italy.
³ Neonatology Intensive Care Unit, Department of Child and Maternal Health, Azienda Ospedaliera - University of Padova, Padova, Italy.

PMID: 26732078
DOI: 10.1016/j.siny.2015.12.001

Abstract

Neonatal anemia is a frequent occurrence in neonatal intensive care units. Red blood cell transfusion criteria in case of blood loss are clearly defined but optimal hemoglobin or hematocrit thresholds of transfusion for anemia due to decreased production or increased destruction are less evident. This review focuses on the causes of anemia in the newborn period and the most recent evidence-based treatment options, including transfusion and erythropoiesis-stimulating agents.

Keywords: Anemia; Neonate; Transfusion; Treatment.

Publication types

Review

MeSH terms

Anemia / diagnosis
Anemia / embryology
Anemia / etiology
Anemia / therapy*
Combined Modality Therapy
Erythrocyte Transfusion*
Erythropoiesis / physiology
Hematinics / therapeutic use
Humans
Infant, Newborn

Substances

Hematinics