Two new tetracyclic triterpenoids from the barks of Melia azedarach

Jun-Jun Ge; Ling-Tian Wang; Pian Chen; Yan Zhang; Xin-Xiang Lei; Xiao-Xia Ye

doi:10.1080/10286020.2015.1124866

Two new tetracyclic triterpenoids from the barks of Melia azedarach

J Asian Nat Prod Res. 2016;18(1):20-5. doi: 10.1080/10286020.2015.1124866. Epub 2016 Jan 4.

Authors

Jun-Jun Ge¹, Ling-Tian Wang², Pian Chen¹, Yan Zhang³, Xin-Xiang Lei³, Xiao-Xia Ye¹

Affiliations

¹ a School of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou 325035 , China.
² b School of Medicine , Shandong University , Jinan 250012 , China.
³ c College of Chemistry & Materials Engineering , Wenzhou University , Wenzhou 325035 , China.

PMID: 26727712
DOI: 10.1080/10286020.2015.1124866

Abstract

Two new tetracyclic triterpenoids, together with 21 known compounds, were isolated from the barks of Melia azedarach. The structures of new compounds were elucidated by the means of HRESIMS, 1D NMR, 2D NMR, and X-ray crystallography analysis.

Keywords: Melia azedarach; Meliaceae; Tetracyclic triterpenoid; antifeedant.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Crystallography, X-Ray
Drugs, Chinese Herbal / chemistry
Drugs, Chinese Herbal / isolation & purification*
Drugs, Chinese Herbal / pharmacology
Melia azedarach / chemistry*
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark / chemistry
Spodoptera / drug effects
Triterpenes / chemistry
Triterpenes / isolation & purification*
Triterpenes / pharmacology

Substances

24-hydroperoxytirucalla-7,25(26)-diene-3,6-dion-21,16-olide
Drugs, Chinese Herbal
Triterpenes
tirucalla-5(6),7,24 (25)-triene-3-dion-21,16-olide