Human compulsivity: A perspective from evolutionary medicine

Eur Neuropsychopharmacol. 2016 May;26(5):869-76. doi: 10.1016/j.euroneuro.2015.12.004. Epub 2015 Dec 10.

Abstract

Biological explanations address not only proximal mechanisms (for example, the underlying neurobiology of obsessive-compulsive disorder), but also distal mechanisms (that is, a consideration of how particular neurobiological mechanisms evolved). Evolutionary medicine has emphasized a series of explanations for vulnerability to disease, including constraints, mismatch, and tradeoffs. The current paper will consider compulsive symptoms in obsessive-compulsive and related disorders and behavioral addictions from this evolutionary perspective. It will argue that while obsessive-compulsive disorder (OCD) is typically best conceptualized as a dysfunction, it is theoretically and clinically valuable to understand some symptoms of obsessive-compulsive and related disorders in terms of useful defenses. The symptoms of behavioral addictions can also be conceptualized in evolutionary terms (for example, mismatch), which in turn provides a sound foundation for approaching assessment and intervention.

Keywords: Evolutionary medicine; Evolutionary psychiatry; Obsessive–compulsive and related disorders; Substance-related and addictive disorders.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Behavior, Addictive
  • Behavior, Animal
  • Biological Evolution*
  • Combined Modality Therapy
  • Compulsive Behavior / diagnosis
  • Compulsive Behavior / physiopathology*
  • Compulsive Behavior / psychology
  • Compulsive Behavior / therapy
  • Compulsive Personality Disorder / diagnosis
  • Compulsive Personality Disorder / physiopathology*
  • Compulsive Personality Disorder / psychology
  • Compulsive Personality Disorder / therapy
  • Defense Mechanisms*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Humans
  • Models, Neurological*
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / physiopathology*
  • Obsessive-Compulsive Disorder / psychology
  • Obsessive-Compulsive Disorder / therapy
  • Psychology, Comparative / methods*
  • Stress, Psychological / physiopathology
  • Stress, Psychological / psychology
  • Substance-Related Disorders / diagnosis
  • Substance-Related Disorders / physiopathology
  • Substance-Related Disorders / psychology
  • Substance-Related Disorders / therapy
  • Terminology as Topic