Beta-1-Selective Beta-Blockers and Cognitive Functions in Patients With Coronary Artery Disease: A Cross-Sectional Study

J Neuropsychiatry Clin Neurosci. 2016 Spring;28(2):143-6. doi: 10.1176/appi.neuropsych.15040088. Epub 2015 Dec 30.

Abstract

The association between current beta-1-selective beta-blocker use and cognitive function was evaluated in 722 patients with coronary artery disease without dementia. Beta-1-selective beta-blocker use was associated with worse incidental learning independently of sociodemographic characteristics, clinical coronary artery disease severity, and depression/anxiety.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / pharmacology*
  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Anxiety / complications
  • Anxiety / psychology
  • Cognition / drug effects*
  • Coronary Artery Disease / complications
  • Coronary Artery Disease / drug therapy*
  • Coronary Artery Disease / psychology
  • Cross-Sectional Studies
  • Depression / complications
  • Depression / psychology
  • Female
  • Humans
  • Learning / drug effects*
  • Male
  • Middle Aged
  • Neuropsychological Tests

Substances

  • Adrenergic beta-Antagonists