Pyoderma Gangrenosum in a Patient with Hereditary Spherocytosis

Int J Low Extrem Wounds. 2016 Mar;15(1):92-5. doi: 10.1177/1534734615623432. Epub 2015 Dec 28.

Abstract

Pyoderma gangrenosum (PG) is a rare, relapsing cutaneous disease with 4 distinctive clinical manifestations: ulcerative, bullous, pustular, and vegetative lesions. It mainly occurs in adults and is frequently associated with systemic diseases, most commonly inflammatory bowel disease, rheumatologic disease, or hematological dyscrasias. However, there have been no previous reports of PG in a patient with hereditary spherocytosis, a common inherited hemolytic anemia. We report here a unique case of PG in a 15-year-old boy with underlying hereditary spherocytosis.

Keywords: hereditary spherocytosis; leg; pyoderma gangrenosum; ulcers.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Humans
  • Leg Ulcer / etiology*
  • Leg Ulcer / pathology
  • Male
  • Pyoderma Gangrenosum / etiology*
  • Pyoderma Gangrenosum / pathology
  • Spherocytosis, Hereditary / complications*