Real-time monitoring of cocrystallization processes by solvent evaporation: A near infrared study

Eur J Pharm Sci. 2016 Jul 30:90:76-84. doi: 10.1016/j.ejps.2015.12.025. Epub 2015 Dec 19.
No abstract available

Keywords: Cocrystal purity; Cocrystallization; Furosemide; Near infrared spectroscopy; Principal components analysis; Real-time monitoring.

MeSH terms

  • 4-Aminobenzoic Acid / chemistry*
  • Computer Systems
  • Crystallization / methods*
  • Furosemide / chemistry*
  • Methanol / chemistry*
  • Solvents / chemistry
  • Spectroscopy, Near-Infrared / methods*
  • Technology, Pharmaceutical / methods
  • Volatilization
  • Water / chemistry*

Substances

  • Solvents
  • Water
  • Furosemide
  • 4-Aminobenzoic Acid
  • Methanol