First report of lukM-positive livestock-associated methicillin-resistant Staphylococcus aureus CC30 from fattening pigs in Northern Ireland

Vet Microbiol. 2016:182:131-4. doi: 10.1016/j.vetmic.2015.11.019. Epub 2015 Nov 18.

Abstract

The increasing number of reports of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) world-wide attests to the public health concern surrounding this pathogen in animal husbandry and in-contact humans. In Europe, LA-MRSA CC398 is predominant and generally regarded as being of low virulence for animals. Herein we report the recovery of a lineage of LA-MRSA, belonging to CC30, from three pigs in Northern Ireland and which encodes a marker of virulence (lukM and lukF-P83) restricted to animal-associated clones of S. aureus.

Keywords: Clonal Complex 30; LA-MRSA; Methicillin-resistant Staphylococcus aureus; Pigs; lukM.

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Gene Expression Regulation, Bacterial
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / metabolism*
  • Northern Ireland / epidemiology
  • Phylogeny
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / veterinary*
  • Swine
  • Swine Diseases / epidemiology
  • Swine Diseases / microbiology*

Substances

  • Bacterial Proteins
  • LukM protein, Staphylococcus aureus