Carbon nanomaterials-based electrochemical aptasensors

Biosens Bioelectron. 2016 May 15:79:136-49. doi: 10.1016/j.bios.2015.11.093. Epub 2015 Dec 1.

Abstract

Carbon nanomaterials (CNMs) have attracted increasing attention due to their unique electrical, optical, thermal, mechanical and chemical properties. CNMs are extensively applied in electronic, optoelectronic, photovoltaic and sensing devices fields, especially in bioassay technology. These excellent properties significantly depend on not only the functional atomic structures of CNMs, but also the interactions with other materials, such as gold nanoparticles, SiO2, chitosan, etc. This review systematically summarizes applications of CNMs in electrochemical aptasensors (ECASs). Firstly, definition and development of ECASs are introduced. Secondly, different ways of ECASs about working principles, classification and construction of CNMs are illustrated. Thirdly, the applications of different CNMs used in ECASs are discussed. In this review, different types of CNMs are involved such as carbon nanotubes, graphene, graphene oxide, etc. Besides, the newly emerging CNMs and CNMs-based composites are also discoursed. Finally, we demonstrate the future prospects of CNMs-based ECASs, and some suggestions about the near future development of CNMs-based ECASs are highlighted.

Keywords: Carbon nanomaterials; Carbon nanotubes; Electrochemical aptasensors; Graphene; Quantum dots.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Aptamers, Nucleotide / chemistry*
  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Carbon / chemistry*
  • Electrochemical Techniques / instrumentation
  • Electrochemical Techniques / methods*
  • Equipment Design
  • Graphite / chemistry
  • Humans
  • Nanostructures / chemistry*
  • Nanostructures / ultrastructure
  • Nanotubes, Carbon / chemistry
  • Nanotubes, Carbon / ultrastructure
  • Quantum Dots / chemistry
  • Quantum Dots / ultrastructure

Substances

  • Aptamers, Nucleotide
  • Nanotubes, Carbon
  • Carbon
  • Graphite