Abstract
When activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.
Keywords:
allylic compounds; boron; heterocycles; samarium iodide; synthetic methods.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Boronic Acids / chemical synthesis*
-
Boronic Acids / chemistry
-
Dihydropyridines / chemical synthesis*
-
Dihydropyridines / chemistry
-
Esters / chemical synthesis*
-
Esters / chemistry
-
Molecular Structure
-
Quantum Theory
Substances
-
Boronic Acids
-
Dihydropyridines
-
Esters
-
1,4-dihydropyridine