Tula hantavirus infection in a hospitalised patient, France, June 2015

Euro Surveill. 2015;20(50). doi: 10.2807/1560-7917.ES.2015.20.50.30095.

Abstract

We report an infection with Tula virus in June 2015, leading to hospitalisation, in a patient living approximately 60 km east of Paris with no previous remarkable medical history. Clinical symptoms were limited to a fever syndrome with severe headache. The main laboratory findings included thrombocytopenia and elevated transaminase levels. Based on S (small) gene sequence analysis, the strain affecting the patient was closely related to strains detected in Central Europe, especially to a south-east German strain.

Keywords: France; clinic; epidemiology; hantavirus; hantavirus infections; laboratory; laboratory surveillance; viral infections; zoonotic infections.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alanine Transaminase / blood
  • Antibodies, Viral / blood
  • C-Reactive Protein / analysis
  • Fever / etiology*
  • Hantavirus Infections / diagnosis*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Male
  • Orthohantavirus / genetics*
  • Orthohantavirus / immunology
  • Orthohantavirus / isolation & purification*
  • Real-Time Polymerase Chain Reaction
  • Sequence Analysis
  • Thrombocytopenia

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M
  • C-Reactive Protein
  • Alanine Transaminase