Physical and Mathematical Modeling in Experimental Papers

Wolfram Möbius; Liedewij Laan

doi:10.1016/j.cell.2015.12.006

Physical and Mathematical Modeling in Experimental Papers

Cell. 2015 Dec 17;163(7):1577-83. doi: 10.1016/j.cell.2015.12.006.

Authors

Wolfram Möbius¹, Liedewij Laan²

Affiliations

¹ Department of Physics and FAS Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: wolfram.moebius@gmail.com.
² Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, 2628 CJ Delft, the Netherlands. Electronic address: l.laan@tudelft.nl.

PMID: 26687351
DOI: 10.1016/j.cell.2015.12.006

Abstract

An increasing number of publications include modeling. Often, such studies help us to gain a deeper insight into the phenomena studied and break down barriers between experimental and theoretical communities. However, combining experimental and theoretical work is challenging for authors, reviewers, and readers. To help maximize the usefulness and impact of combined theoretical and experimental research, this Primer describes the purpose, usefulness, and different types of models and addresses the practical aspect of integrated publications by outlining characteristics of good modeling, presentation, and fruitful collaborations.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Bacterial Physiological Phenomena
Cell Physiological Phenomena
Computer Simulation*
Models, Biological*
Models, Chemical
Proteins / chemistry
Proteins / physiology

Substances

Proteins