Induction Therapy for Mesothelioma

Semin Thorac Cardiovasc Surg. 2015 Summer;27(2):240-9. doi: 10.1053/j.semtcvs.2015.05.003. Epub 2015 Jun 17.

Abstract

One particular approach of multimodality treatment for mesothelioma is induction therapy followed by surgery. Among its several advantages, the most important is downstaging of the tumor into a resectable stage, although morbidity and mortality might be increased. In this article we review the principles and outcome of different modalities for induction treatment of mesothelioma.

Keywords: Extrapleural Pneumonectomy.; MCR; MPM; Pleurectomy and Decortication; induction therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biopsy
  • Chemotherapy, Adjuvant
  • Humans
  • Induction Chemotherapy* / adverse effects
  • Induction Chemotherapy* / mortality
  • Kaplan-Meier Estimate
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy*
  • Mesothelioma / diagnostic imaging
  • Mesothelioma / mortality
  • Mesothelioma / pathology
  • Mesothelioma / therapy*
  • Mesothelioma, Malignant
  • Neoadjuvant Therapy* / adverse effects
  • Neoadjuvant Therapy* / mortality
  • Neoplasm Staging
  • Pneumonectomy* / adverse effects
  • Pneumonectomy* / mortality
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome