Occurrence of deoxynivalenol in wheat, Hebei Province, China

Yinping Liu; Yang Lu; Liying Wang; Fengqi Chang; Lixin Yang

doi:10.1016/j.foodchem.2015.11.047

Occurrence of deoxynivalenol in wheat, Hebei Province, China

Food Chem. 2016 Apr 15:197 Pt B:1271-4. doi: 10.1016/j.foodchem.2015.11.047. Epub 2015 Nov 11.

Authors

Yinping Liu¹, Yang Lu¹, Liying Wang¹, Fengqi Chang¹, Lixin Yang²

Affiliations

¹ Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang 050021, PR China.
² Hebei Provincial Center for Disease Control and Prevention, Shijiazhuang 050021, PR China. Electronic address: yanglixin241@163.com.

PMID: 26675867
DOI: 10.1016/j.foodchem.2015.11.047

Abstract

Analysis of deoxynivalenol (DON) and its metabolites 3-acetyl and 15-acetyldeoxynivalenol (3-ADON and 15-ADON) in wheat flour samples by liquid chromatography-tandem mass spectrometry (LC/MS/MS) during 2011-2013 was conducted. [(13)C15]-DON was used as the internal standard to accomplish as accurate as possible quantitation. Of all wheat samples (n=672), 91.5% were positive for DON, at levels ranging from 2.4 to 1130 μg/kg, with a median value of 154 μg/kg. The DON derivatives (3-Ac-DON, 15-Ac-DON) were far less frequently found and at lower levels than DON. The probable daily intakes (PDI) of DON (0.49 in 2011; 0.86 in 2012; 0.56 in 2013, expressed as μg/kg body weight/day) were all within the PDI of 1.0 μg/kg of bw/day for DON set by Scientific Committee for Food (SCF) in 2002. Still, persistent monitoring of DON is important.

Keywords: China; Deoxynivalenol; LC/MS/MS; Wheat flour.

MeSH terms

Chromatography, Liquid / methods
Flour / analysis
Humans
Risk Assessment
Tandem Mass Spectrometry / methods
Trichothecenes / analysis*
Triticum / chemistry*

Substances

Trichothecenes
3-acetyldeoxynivalenol
15-acetyldeoxynivalenol
deoxynivalenol