Therapeutic role of endoscopic ultrasound in pancreaticobiliary disease: A comprehensive review

World J Gastroenterol. 2015 Dec 14;21(46):12996-3003. doi: 10.3748/wjg.v21.i46.12996.

Abstract

With the development of technology and accessories, the role of endoscopic ultrasound (EUS) has evolved from diagnostics to therapeutics. In order to characterise the therapeutic role of EUS, we searched Web of Knowledge database and reviewed articles associated with therapeutic EUS. There are two modalities for the therapeutic purpose: drainage and fine-needle injection. EUS-guided drainage is a promising procedure for the treatment of peripancreatic fluid collection and biliary obstruction; EUS-guided fine-needle injections such as celiac plexus neurolysis, for the purpose of pain relief for pancreatic cancer and chronic pancreatitis, has emerged as a promising procedure. The aim of the study was to perform a comprehensive and conscientious review on the techniques, complications and clinical outcomes of those EUS-based procedures.

Keywords: Biliary drainage; Celiac plexus neurolysis; Endoscopic ultrasound; Peripancreatic fluid collection; Therapeutic.

Publication types

  • Review

MeSH terms

  • Biliary Tract Diseases / diagnostic imaging
  • Biliary Tract Diseases / therapy*
  • Drainage / adverse effects
  • Drainage / methods*
  • Endosonography* / adverse effects
  • Humans
  • Injections
  • Nerve Block / adverse effects
  • Nerve Block / methods*
  • Pancreatic Diseases / diagnostic imaging
  • Pancreatic Diseases / therapy*
  • Risk Factors
  • Sensory System Agents / administration & dosage
  • Treatment Outcome
  • Ultrasonography, Interventional / adverse effects
  • Ultrasonography, Interventional / methods*

Substances

  • Sensory System Agents