Carbon dots on based folic acid coated with PAMAM dendrimer as platform for Pt(IV) detection

Bruno B Campos; María Moreno Oliva; Rafael Contreras-Cáceres; Enrique Rodriguez-Castellón; José Jiménez-Jiménez; Joaquim C G Esteves da Silva; Manuel Algarra

doi:10.1016/j.jcis.2015.11.059

Carbon dots on based folic acid coated with PAMAM dendrimer as platform for Pt(IV) detection

J Colloid Interface Sci. 2016 Mar 1:465:165-73. doi: 10.1016/j.jcis.2015.11.059. Epub 2015 Nov 24.

Authors

Bruno B Campos¹, María Moreno Oliva², Rafael Contreras-Cáceres³, Enrique Rodriguez-Castellón⁴, José Jiménez-Jiménez⁴, Joaquim C G Esteves da Silva¹, Manuel Algarra⁵

Affiliations

¹ Centro de Investigação em Química, Departamento de Geociencias, ambiente e ordenamento do territorio, Faculdade de Ciências da, Universidade do Porto, Porto, Portugal.
² Departamento de Química Física, Facultad de Ciencias, Universidad de Málaga, Campus de Teatinos s/n, 29071 Málaga, Spain.
³ Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Málaga, Campus de Teatinos s/n, 29071 Málaga, Spain.
⁴ Departamento de Química Inorgánica, Universidad de Málaga, Campus de Teatinos s/n, 29071 Málaga, Spain.
⁵ Departamento de Química Inorgánica, Universidad de Málaga, Campus de Teatinos s/n, 29071 Málaga, Spain. Electronic address: malgarra67@gmail.com.

PMID: 26674232
DOI: 10.1016/j.jcis.2015.11.059

Abstract

Carbon quantum dots (CQDs) coated with poly(amidoamine) (PAMAM-NH2) dendrimer are prepared from folic acid and phosphoric acid under a hydrothermal procedure. The obtained nanoparticles are successfully used as fluorescent sensor for Pt(IV) (in the form of chloroplatinate ion). CQDs possess many attractive features including uniform dispersion with average size about 13nm for unmodified particles and, ∼30nm when they are coated with PAMAM-NH2 dendrimer. The synthesized nanoparticles have been characterized by elemental analysis, attenuated total reflectance (ATR), X-ray photoelectron (XPS) and Raman spectroscopies, transmission electron microscopy (TEM), dynamic light scattering (DLS), and steady-state and life-time fluorescence. CQDs are used as fluorescent sensor of Pt(IV) ion in aqueous media showing linear quenching effect of their fluorescence. The results obtained demonstrated a limit of detection of 657nM with an accuracy of the method of 0.13% (as RSD, n=10) and sensitivity of 78nM. Moreover, with the presence of other interference species, good results are obtained when applied in real samples from platinum nanoparticles synthesis. The dissolved platinum ions can be quantified in the range 6-96μM with an accuracy of 2.5%.

Keywords: Carbon quantum dots; Chloroplatinate ion; Dendrimer; Doped nanoparticles; Sensor.