Partial splenic embolization of patients with hypersplenism by transradial or transfemoral approach: a prospective randomized controlled trial

Acta Radiol. 2016 Oct;57(10):1201-4. doi: 10.1177/0284185115622076. Epub 2015 Dec 14.

Abstract

Background: Partial splenic artery embolization (PSE) is an effective treatment modality for patients with hypersplenism. It is less invasive and has a quicker recovery compared with surgical procedures. PSE is usually performed using a femoral artery approach that requires bedrest for a few hours, which is rarely the case for transradial PSE.

Purpose: To compare the transradial and transfemoral approaches for embolization of spleen in patients with hypersplenism.

Material and methods: In all, 84 patients with hypersplenism who required PSE were recruited. They were randomly divided into two groups on the basis of the procedure followed: the transradial approach (R-PSE, n = 39) or transfemoral approach (F-PSE, n = 45). Technical success, puncture rate, total procedure time, X-ray exposure time, length of stay in hospital (LOS), and complications of the two groups were recorded.

Results: The procedure time, X-ray exposure time, and LOS were found to be lower in the R-PSE group than in the F-PSE. However, this difference was not statistically significant.

Conclusion: The transradial artery approach for PSE in patients with hypersplenism is feasible with no major complications as compared to the femoral approach.

Keywords: Partial splenic embolization; cirrhosis; hypersplenism; radial artery approach; transfemoral approach.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Diagnostic Imaging
  • Embolization, Therapeutic / methods*
  • Female
  • Femoral Artery
  • Humans
  • Hypersplenism / diagnostic imaging
  • Hypersplenism / etiology
  • Hypersplenism / therapy*
  • Length of Stay / statistics & numerical data
  • Liver Cirrhosis / complications
  • Male
  • Middle Aged
  • Prospective Studies
  • Radial Artery
  • Radiography, Interventional
  • Time Factors
  • Treatment Outcome