Complete Genome Sequencing of Stenotrophomonas acidaminiphila ZAC14D2_NAIMI4_2, a Multidrug-Resistant Strain Isolated from Sediments of a Polluted River in Mexico, Uncovers New Antibiotic Resistance Genes and a Novel Class-II Lasso Peptide Biosynthesis Gene Cluster

Pablo Vinuesa; Luz Edith Ochoa-Sánchez

doi:10.1128/genomeA.01433-15

Complete Genome Sequencing of Stenotrophomonas acidaminiphila ZAC14D2_NAIMI4_2, a Multidrug-Resistant Strain Isolated from Sediments of a Polluted River in Mexico, Uncovers New Antibiotic Resistance Genes and a Novel Class-II Lasso Peptide Biosynthesis Gene Cluster

Genome Announc. 2015 Dec 10;3(6):e01433-15. doi: 10.1128/genomeA.01433-15.

Authors

Pablo Vinuesa¹, Luz Edith Ochoa-Sánchez²

Affiliations

¹ Centro de Ciencias Genómicas, Programa de Ingeniería Genómica, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico vinuesa@ccg.unam.mx.
² Centro de Ciencias Genómicas, Programa de Ingeniería Genómica, Universidad Nacional Autónoma de México, Cuernavaca, Morelos, Mexico.

Abstract

Here, we report the first complete genome sequence of a Stenotrophomonas acidaminiphila strain, generated with PacBio RS II single-molecule real-time technology, consisting of a single circular chromosome of 4.13 Mb. We annotated mobile genetic elements and natural product biosynthesis clusters, including a novel class-II lasso peptide with a 7-residue macrolactam ring.