Conjunctival Sensation in Scleritis

Ocul Immunol Inflamm. 2016;24(1):24-8. doi: 10.3109/09273948.2015.1057598. Epub 2015 Dec 8.

Abstract

Purpose: To investigate conjunctival sensation in patients with scleritis.

Methods: Retrospective cross-sectional study of patients with scleritis. Conjunctival sensation was tested by Cochet-Bonnet aesthesiometer in four quadrants of the bulbar conjunctiva plus the area(s) of active or previously active inflammation; sensation was compared with the contralateral eye.

Results: Of 28 patients with scleritis, nine had active scleritis and 19 had inactive scleritis. Eleven patients had a systemic autoimmune condition and five had infectious scleritis. The mean conjunctival sensation score of areas of inactive scleritis was significantly less than that of corresponding normal areas in the contralateral eye (p<0.001). Among patients with presumed herpetic scleritis, conjunctival sensation was significantly lower in the affected eye than in the unaffected eye (p<0.001).

Conclusions: Conjunctival sensation is decreased in areas of previously active inflammation from scleritis. Eyes with herpetic scleritis had reduced conjunctival sensation, even in areas without previous active inflammation.

Keywords: Cochet-Bonnet aesthesiometer; conjunctival sensation; corneal sensation; scleritis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Conjunctiva / physiopathology*
  • Cornea / physiopathology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypesthesia / physiopathology
  • Keratitis, Herpetic / diagnosis
  • Keratitis, Herpetic / physiopathology
  • Keratitis, Herpetic / virology
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / diagnosis
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Mycobacterium Infections, Nontuberculous / physiopathology
  • Mycobacterium chelonae / isolation & purification
  • Retrospective Studies
  • Scleritis / diagnosis
  • Scleritis / microbiology
  • Scleritis / physiopathology*
  • Scleritis / virology
  • Vitreous Body / microbiology