Colorectal cancer (CRC) is the most common cancer in digestive system, with the highest mortality rate. Its pathogenesis, diagnosis and treatment have been studied extensively. With the deepening of the investigations, more and more studies show that miRNA is closely related with the carcinogenesis, diagnosis and treatment of CRC. The abnormal expression of blood miRNA is expected to become the biomarkers for early diagnosis of CRC and prognostic evaluation, and it may provide a new strategy for clinical treatment.
结直肠癌是目前最常见的也是病死率最高的消化系统恶性肿瘤之一，其发病机制、诊断及治疗等已被广泛研究。随着研究的不断深入，近年来越来越多的研究表明微小RNA(microRNA，miRNA)与结直肠癌发生、诊断、治疗等均有密切关系，血液中异常表达的miRNA有望成为结直肠癌早期诊断和预后的标志物，并且可为临床提供新的治疗思路。.