Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene

Amalia Barreto-Luis; Maria Pino-Yanes; Almudena Corrales; Paloma Campo; Ariel Callero; Marialbert Acosta-Herrera; José Cumplido; Shwu-Fan Ma; Juan Martinez-Tadeo; Jesús Villar; Joe G N Garcia; Teresa Carrillo; Ángel Carracedo; Miguel Blanca; Carlos Flores

doi:10.1016/j.jaci.2015.09.051

Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene

J Allergy Clin Immunol. 2016 Mar;137(3):964-6. doi: 10.1016/j.jaci.2015.09.051. Epub 2015 Nov 24.

Authors

Affiliations

¹ Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; Applied Genomics Group (G2A), Genetics Laboratory, Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (CIBICAN), Universidad de La Laguna, Tenerife, Spain.
² Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
³ U.G.C. Allergy, Regional University Hospital of Málaga-IBIMA, Málaga, Spain.
⁴ Allergy Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain.
⁵ Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Multidisciplinary Organ Dysfunction Evaluation Research Network (MODERN), Research Unit, Hospital Universitario Dr Negrin, Gran Canaria, Spain.
⁶ Allergy Unit, Hospital Universitario Dr Negrin, Gran Canaria, Spain.
⁷ Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Ill.
⁸ CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Multidisciplinary Organ Dysfunction Evaluation Research Network (MODERN), Research Unit, Hospital Universitario Dr Negrin, Gran Canaria, Spain.
⁹ Arizona Health Sciences Center, University of Arizona, Tucson, Ariz.
¹⁰ Grupo de Medicina Xenómica, CIBERER-Universidade de Santiago de Compostela-Fundación Galega de Medicina Xenómica (SERGAS), Santiago de Compostela, Spain.
¹¹ Research Unit, Hospital Universitario N.S. de Candelaria, Tenerife, Spain; Applied Genomics Group (G2A), Genetics Laboratory, Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (CIBICAN), Universidad de La Laguna, Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. Electronic address: cflores@ull.edu.es.

PMID: 26620591
DOI: 10.1016/j.jaci.2015.09.051

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

ADAM Proteins / genetics*
ADAMTS9 Protein
Asthma / genetics*
Case-Control Studies
Genetic Association Studies
Genetic Predisposition to Disease*
Genome-Wide Association Study*
Humans
Polymorphism, Single Nucleotide
Spain
White People / genetics*

Substances

ADAM Proteins
ADAMTS9 Protein
ADAMTS9 protein, human